![]() Academic research based on this model enables the training and development of practical, scientific, and leadership skills in Industrial Pharmacy students. The QbD model stands out as a great methodology for carrying out research projects regarding Pharmaceutical Sciences, but especially for Industrial Pharmacy, where it has contributed in terms of formulation development, manufacturing, and quality control. Institutional repositories from the different universities were reviewed as well. Pubmed, Science Direct, and Google Scholar databases were screened for original research papers and review papers published not more than ten years ago. This review aims to present the Quality by Design (QbD) model as a suitable methodology to perform research in the academic Costa Rican institutions that teach Pharmacy. ![]() Overall, then, fishbone diagram seems to be an appropriate and general technique of graphical representation to explore and categorize, clearly and simply, the potential root causes of the evolution of technological innovations for an appropriate management of technology. Fishbone diagram is applied here as a novel graphical representation to identify, explore and analyse whenever possible, the potential root causes of the source and evolution of General Purpose Technologies (GPTs). The fishbone diagram can be a comprehensive theoretical framework to represent and analyze the sources of innovation. In particular, a fishbone diagram (the shape is similar to a fish skeleton) is a common tool used for a cause and effect analysis to identify a complex interplay of causes for a specific problem or event. Fishbone diagram (also called Ishikawa diagrams or cause-and-effect diagrams) is a graphical technique to show the several causes of a specific event or phenomenon. This study suggests the fishbone diagram for technological analysis.
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